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GATA3 Promotes the Neural Progenitor State but Not Neurogenesis in 3D Traumatic Injury Model of Primary Human Cortical Astrocytes

Astrocytes are abundant cell types in the vertebrate central nervous system and can act as neural stem cells in specialized niches where they constitutively generate new neurons. Outside the stem cell niches, however, these glial cells are not neurogenic. Although injuries in the mammalian central n...

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Detalles Bibliográficos
Autores principales: Celikkaya, Hilal, Cosacak, Mehmet Ilyas, Papadimitriou, Christos, Popova, Stanislava, Bhattarai, Prabesh, Biswas, Srijeeta Nag, Siddiqui, Tohid, Wistorf, Sabrina, Nevado-Alcalde, Isabel, Naumann, Lisa, Mashkaryan, Violeta, Brandt, Kerstin, Freudenberg, Uwe, Werner, Carsten, Kizil, Caghan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380212/
https://www.ncbi.nlm.nih.gov/pubmed/30809125
http://dx.doi.org/10.3389/fncel.2019.00023