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Division of labour: tRNA methylation by the NSun2 tRNA methyltransferases Trm4a and Trm4b in fission yeast

Enzymes of the cytosine-5 RNA methyltransferase Trm4/NSun2 family methylate tRNAs at C48 and C49 in multiple tRNAs, as well as C34 and C40 in selected tRNAs. In contrast to most other organisms, fission yeast Schizosaccharomyces pombe carries two Trm4/NSun2 homologs, Trm4a (SPAC17D4.04) and Trm4b (S...

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Detalles Bibliográficos
Autores principales: Müller, Martin, Samel-Pommerencke, Anke, Legrand, Carine, Tuorto, Francesca, Lyko, Frank, Ehrenhofer-Murray, Ann E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380293/
https://www.ncbi.nlm.nih.gov/pubmed/30646830
http://dx.doi.org/10.1080/15476286.2019.1568819