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Bi-phased regulation of the post-transcriptional inflammatory response by Tristetraprolin levels

AU-rich elements (AREs) are cis-acting instability and translation inhibition elements that are present in the 3ʹUTR of most inducible inflammatory mRNAs such as TNF and Cxcl2. mRNAs that contain AREs are, by default, repressed and only transiently expressed in response to stimuli. They are targeted...

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Detalles Bibliográficos
Autores principales: Mahmoud, Linah, Moghrabi, Walid, Khabar, Khalid S. A., Hitti, Edward G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380337/
https://www.ncbi.nlm.nih.gov/pubmed/30664390
http://dx.doi.org/10.1080/15476286.2019.1572437