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Developmental regulation of DNA cytosine methylation at the immunoglobulin heavy chain constant locus

DNA cytosine methylation is involved in the regulation of gene expression during development and its deregulation is often associated with disease. Mammalian genomes are predominantly methylated at CpG dinucleotides. Unmethylated CpGs are often associated with active regulatory sequences while methy...

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Detalles Bibliográficos
Autores principales: Oudinet, Chloé, Braikia, Fatima-Zohra, Dauba, Audrey, Santos, Joana M., Khamlichi, Ahmed Amine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380546/
https://www.ncbi.nlm.nih.gov/pubmed/30779742
http://dx.doi.org/10.1371/journal.pgen.1007930