Cargando…

Developmental regulation of DNA cytosine methylation at the immunoglobulin heavy chain constant locus

DNA cytosine methylation is involved in the regulation of gene expression during development and its deregulation is often associated with disease. Mammalian genomes are predominantly methylated at CpG dinucleotides. Unmethylated CpGs are often associated with active regulatory sequences while methy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oudinet, Chloé, Braikia, Fatima-Zohra, Dauba, Audrey, Santos, Joana M., Khamlichi, Ahmed Amine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380546/ https://www.ncbi.nlm.nih.gov/pubmed/30779742 http://dx.doi.org/10.1371/journal.pgen.1007930

Ejemplares similares

Recombination may occur in the absence of transcription in the immunoglobulin heavy chain recombination centre
por: Oudinet, Chloé, et al.
Publicado: (2020)

Duplication of a germline promoter downstream of the IgH 3′ regulatory region impairs class switch recombination
por: Santos, Joana M., et al.
Publicado: (2018)

Switch Tandem Repeats Influence the Choice of the Alternative End-Joining Pathway in Immunoglobulin Class Switch Recombination
por: Oudinet, Chloé, et al.
Publicado: (2022)

Essential role of the initial activation signal in isotype selection upon deletion of a transcriptionally committed promoter
por: Santos, Joana M., et al.
Publicado: (2019)

Long-Range Control of Class Switch Recombination by Transcriptional Regulatory Elements
por: Dauba, Audrey, et al.
Publicado: (2021)

Population-specific diversity of the immunoglobulin constant heavy G chain (IGHG) genes
por: Bashirova, Arman A., et al.
Publicado: (2021)

Organization of the variable region of the immunoglobulin heavy-chain gene locus of the rat
por: Hendricks, Jacobus, et al.
Publicado: (2010)

The Complete Nucleotide Sequence of the Human Immunoglobulin Heavy Chain Variable Region Locus
por: Matsuda, Fumihiko, et al.
Publicado: (1998)

Genetic variation in the immunoglobulin heavy chain locus shapes the human antibody repertoire
por: Rodriguez, Oscar L., et al.
Publicado: (2023)

Epigenetic Regulation of Individual Modules of the immunoglobulin heavy chain locus 3′ Regulatory Region
por: Birshtein, Barbara K.
Publicado: (2014)

Extreme genomic volatility characterizes the evolution of the immunoglobulin heavy chain locus in cyprinodontiform fishes
por: Bradshaw, William J., et al.
Publicado: (2020)

Regulation of DNA Replication within the Immunoglobulin Heavy-Chain Locus During B Cell Commitment
por: Demczuk, Agnieszka, et al.
Publicado: (2012)

Estimating Copy Number and Allelic Variation at the Immunoglobulin Heavy Chain Locus Using Short Reads
por: Luo, Shishi, et al.
Publicado: (2016)

A Novel Framework for Characterizing Genomic Haplotype Diversity in the Human Immunoglobulin Heavy Chain Locus
por: Rodriguez, Oscar L., et al.
Publicado: (2020)

Allelic exclusion of the immunoglobulin heavy chain locus is independent of its nuclear localization in mature B cells
por: Holwerda, Sjoerd J. B., et al.
Publicado: (2013)

The 3′ end of the heavy chain constant region locus enhances germline transcription and switch recombination of the four γ genes
por: Dunnick, Wesley A., et al.
Publicado: (2005)

Immunoglobulin Heavy Chain Exclusion in the Shark
por: Malecek, Karolina, et al.
Publicado: (2008)

A 220-nucleotide deletion of the intronic enhancer reveals an epigenetic hierarchy in immunoglobulin heavy chain locus activation
por: Chakraborty, Tirtha, et al.
Publicado: (2009)

Immunoglobulin heavy chains in medaka (Oryzias latipes)
por: Magadán-Mompó, Susana, et al.
Publicado: (2011)

Expression of an idiotype (Id-460) during in vivo anti-dinitrophenyl antibody responses. I. Mapping of genes for Id-460 expression to the variable region of immunoglobulin heavy-chain locus and to the variable region of immunoglobulin kappa-light-chain locus
Publicado: (1980)

Assembly and secretion of heavy chains that do not associate posttranslationally with immunoglobulin heavy chain-binding protein
Publicado: (1987)

Transgenes of the Mouse Immunoglobulin Heavy Chain Locus, Lacking Distal Elements in the 3′ Regulatory Region, Are Impaired for Class Switch Recombination
por: Dunnick, Wesley A., et al.
Publicado: (2013)

The T suppressor cell alloantigen Tsud maps near immunoglobulin allotype genes and may be an heavy chain constant-region marker on a T cell receptor
Publicado: (1981)

Somatic hypermutation of an immunoglobulin mu heavy chain transgene
Publicado: (1993)

Maturation of the Human Immunoglobulin Heavy Chain Repertoire With Age
por: Ghraichy, Marie, et al.
Publicado: (2020)

Chromosomal location of human kappa and lambda immunoglobulin light chain constant region genes
por: McBride, OW, et al.
Publicado: (1982)

Posttranslational association of immunoglobulin heavy chain binding protein with nascent heavy chains in nonsecreting and secreting hybridomas
Publicado: (1986)

Two distinct allotypic determinants on the antigen-specific suppressor and enhancing T cell factors that are encoded by genes linked to the immunoglobulin heavy chain locus
Publicado: (1982)

The Transcriptional Promoter Regulates Hypermutation of the Antibody Heavy Chain Locus
por: Tumas-Brundage, Kathleen, et al.
Publicado: (1997)

Monoclonal immunoglobulin heavy chain gene rearrangement in Fuchs’ uveitis
por: Nakahara, Hisae, et al.
Publicado: (2018)

Immunoglobulin Heavy Chain Gene Rearrangements in Patients with Gaucher Disease
por: Rodić, Predrag, et al.
Publicado: (2018)

Functional humanization of immunoglobulin heavy constant gamma 1 Fc domain human FCGRT transgenic mice
por: Low, Benjamin E., et al.
Publicado: (2020)

Immunoglobulin heavy chain and binding protein complexes are dissociated in vivo by light chain addition
Publicado: (1990)

Altered 3D chromatin structure permits inversional recombination at the IgH locus
por: Qiu, Xiang, et al.
Publicado: (2020)

Generation of immunoglobulin heavy chain diversity subsequent to cell surface immunoglobulin expression in the avian bursa of Fabricius
Publicado: (1989)

ImmunoGlobulin galaxy (IGGalaxy) for simple determination and quantitation of immunoglobulin heavy chain rearrangements from NGS
por: Moorhouse, Michael J, et al.
Publicado: (2014)

A deletion map of the human immunoglobulin heavy chain variable region
Publicado: (1991)

IMMUNOSUPPRESSION OF MICE INJECTED WITH HETEROLOGOUS ANTI-IMMUNOGLOBULIN HEAVY CHAIN ANTISERA
por: Manning, Dean D., et al.
Publicado: (1972)

Genetic linkage of the cytolytic T lymphocyte repertoire and immunoglobulin heavy chain genes
Publicado: (1982)

Organization, structure, and assembly of immunoglobulin heavy chain diversity DNA segments
Publicado: (1982)

Cannot write session to /tmp/vufind_sessions/sess_n7esps7h6ijb65a6ronh6rtl9v