The knocking down of the oncoprotein Golgi phosphoprotein 3 in T98G cells of glioblastoma multiforme disrupts cell migration by affecting focal adhesion dynamics in a focal adhesion kinase-dependent manner

Golgi phosphoprotein 3 (GOLPH3) is a conserved protein of the Golgi apparatus that in humans has been implicated in tumorigenesis. However, the precise function of GOLPH3 in malignant transformation is still unknown. Nevertheless, clinicopathological data shows that in more than a dozen kinds of can...

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Detalles Bibliográficos
Autores principales: Arriagada, Cecilia, Luchsinger, Charlotte, González, Alexis E., Schwenke, Tomás, Arriagada, Gloria, Folch, Hugo, Ehrenfeld, Pamela, Burgos, Patricia V., Mardones, Gonzalo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380552/
https://www.ncbi.nlm.nih.gov/pubmed/30779783
http://dx.doi.org/10.1371/journal.pone.0212321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380552/
https://www.ncbi.nlm.nih.gov/pubmed/30779783
http://dx.doi.org/10.1371/journal.pone.0212321

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