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S100A4 inhibits cell proliferation by interfering with the S100A1-RAGE V domain

The Ca(2+)-dependent human S100A4 (Mts1) protein is part of the S100 family. Here, we studied the interactions of S100A4 with S100A1 using nuclear magnetic resonance (NMR) spectroscopy. We used the chemical shift perturbed residues from HSQC to model S100A4 and S100A1 complex with HADDOCK software....

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Detalles Bibliográficos
Autores principales: Khan, Md. Imran, Yuan, Tai, Chou, Ruey-Hwang, Yu, Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380570/
https://www.ncbi.nlm.nih.gov/pubmed/30779808
http://dx.doi.org/10.1371/journal.pone.0212299