Subunits of the mechano-electrical transduction channel, Tmc1/2b, require Tmie to localize in zebrafish sensory hair cells

Mutations in transmembrane inner ear (TMIE) cause deafness in humans; previous studies suggest involvement in the mechano-electrical transduction (MET) complex in sensory hair cells, but TMIE’s precise role is unclear. In tmie zebrafish mutants, we observed that GFP-tagged Tmc1 and Tmc2b, which are...

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Detalles Bibliográficos
Autores principales: Pacentine, Itallia V., Nicolson, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380590/
https://www.ncbi.nlm.nih.gov/pubmed/30726219
http://dx.doi.org/10.1371/journal.pgen.1007635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380590/
https://www.ncbi.nlm.nih.gov/pubmed/30726219
http://dx.doi.org/10.1371/journal.pgen.1007635

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