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Glucocorticoids and checkpoint tyrosine kinase inhibitors stimulate rat pancreatic beta cell proliferation differentially

Cell therapy for diabetes could benefit from the identification of small-molecule compounds that increase the number of functional pancreatic beta cells. Using a newly developed screening assay, we previously identified glucocorticoids as potent stimulators of human and rat beta cell proliferation....

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Detalles Bibliográficos
Autores principales: Akbib, Sarah, Stichelmans, Jordy, Stangé, Geert, Ling, Zhidong, Assefa, Zerihun, Hellemans, Karine H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380609/
https://www.ncbi.nlm.nih.gov/pubmed/30779812
http://dx.doi.org/10.1371/journal.pone.0212210