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Glucocorticoids and checkpoint tyrosine kinase inhibitors stimulate rat pancreatic beta cell proliferation differentially
Cell therapy for diabetes could benefit from the identification of small-molecule compounds that increase the number of functional pancreatic beta cells. Using a newly developed screening assay, we previously identified glucocorticoids as potent stimulators of human and rat beta cell proliferation....
Autores principales: | Akbib, Sarah, Stichelmans, Jordy, Stangé, Geert, Ling, Zhidong, Assefa, Zerihun, Hellemans, Karine H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380609/ https://www.ncbi.nlm.nih.gov/pubmed/30779812 http://dx.doi.org/10.1371/journal.pone.0212210 |
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