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Dynamics of ACTH-Mediated Regulation of Gene Transcription in ATC1 and ATC7 Adrenal Zona Fasciculata Cell Lines

We tested the hypothesis that mouse ATC1 and ATC7 cells, the first adrenocortical cell lines to exhibit a complete zona fasciculata (ZF) cell phenotype, respond to dynamic ACTH stimulation in a similar manner as the adrenal gland in vivo. Exploiting our previous in vivo observations that gene transc...

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Detalles Bibliográficos
Autores principales: Hazell, Georgina, Horn, George, Lightman, Stafford L, Spiga, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380881/
https://www.ncbi.nlm.nih.gov/pubmed/30768667
http://dx.doi.org/10.1210/en.2018-00840