Temporal enhancer profiling of parallel lineages identifies AHR and GLIS1 as regulators of mesenchymal multipotency

Temporal data on gene expression and context-specific open chromatin states can improve identification of key transcription factors (TFs) and the gene regulatory networks (GRNs) controlling cellular differentiation. However, their integration remains challenging. Here, we delineate a general approac...

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Detalles Bibliográficos
Autores principales: Gérard, Deborah, Schmidt, Florian, Ginolhac, Aurélien, Schmitz, Martine, Halder, Rashi, Ebert, Peter, Schulz, Marcel H, Sauter, Thomas, Sinkkonen, Lasse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380961/
https://www.ncbi.nlm.nih.gov/pubmed/30544251
http://dx.doi.org/10.1093/nar/gky1240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380961/
https://www.ncbi.nlm.nih.gov/pubmed/30544251
http://dx.doi.org/10.1093/nar/gky1240

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