Probing Anti-inflammatory Properties Independent of NF-κB Through Conformational Constraint of Peptide-Based Interleukin-1 Receptor Biased Ligands

Interleukin-1β (IL-1β) binds to the IL-1 receptor (IL-1R) and is a key cytokine mediator of inflammasome activation. IL-1β signaling leads to parturition in preterm birth (PTB) and contributes to the retinal vaso-obliteration characteristic of oxygen-induced retinopathy (OIR) of premature infants. T...

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Detalles Bibliográficos
Autores principales: Geranurimi, Azade, Cheng, Colin W. H., Quiniou, Christiane, Zhu, Tang, Hou, Xin, Rivera, José Carlos, St-Cyr, Daniel J., Beauregard, Kim, Bernard-Gauthier, Vadim, Chemtob, Sylvain, Lubell, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381024/
https://www.ncbi.nlm.nih.gov/pubmed/30815434
http://dx.doi.org/10.3389/fchem.2019.00023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381024/
https://www.ncbi.nlm.nih.gov/pubmed/30815434
http://dx.doi.org/10.3389/fchem.2019.00023

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