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Antitumor Potential of Extracellular Vesicles Released by Genetically Modified Murine Colon Carcinoma Cells With Overexpression of Interleukin-12 and shRNA for TGF-β1

Recent developments demonstrate that tumor-derived extracellular vesicles (EVs) could become a highly effective tool for delivery of antitumor factors. The main objective of the study was to determine whether EVs secreted by MC38 colon carcinoma cells genetically engineered for overproduction of int...

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Detalles Bibliográficos
Autores principales: Rossowska, Joanna, Anger, Natalia, Wegierek, Katarzyna, Szczygieł, Agnieszka, Mierzejewska, Jagoda, Milczarek, Magdalena, Szermer-Olearnik, Bożena, Pajtasz-Piasecka, Elżbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381037/
https://www.ncbi.nlm.nih.gov/pubmed/30814999
http://dx.doi.org/10.3389/fimmu.2019.00211