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Analysis of postmarketing safety data for proton-pump inhibitors reveals increased propensity for renal injury, electrolyte abnormalities, and nephrolithiasis

Proton pump inhibitors, PPIs, are widely prescribed and sold globally. Although initially intended for time-limited treatment of acute disorders, such as gastric ulcers and esophagitis, PPIs are now commonly used for prolonged durations and are considered safe for over the counter access. Recent stu...

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Detalles Bibliográficos
Autores principales: Makunts, Tigran, Cohen, Isaac V., Awdishu, Linda, Abagyan, Ruben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381091/
https://www.ncbi.nlm.nih.gov/pubmed/30783195
http://dx.doi.org/10.1038/s41598-019-39335-7