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Recycling endosomal CD133 functions as an inhibitor of autophagy at the pericentrosomal region

CD133 is a transmembranous protein that mainly localises to the plasma membrane in haematopoietic and neural stem cells as well as cancer stem cells. Although CD133 also localises to the cytoplasm, the mechanism of action and function of cytoplasmic CD133 currently remain unknown. We herein demonstr...

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Detalles Bibliográficos
Autores principales: Izumi, Hideki, Li, Yuanyuan, Shibaki, Masami, Mori, Daisuke, Yasunami, Michio, Sato, Seiji, Matsunaga, Hisashi, Mae, Takao, Kodama, Kenji, Kamijo, Takehiko, Kaneko, Yasuhiko, Nakagawara, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381095/
https://www.ncbi.nlm.nih.gov/pubmed/30783186
http://dx.doi.org/10.1038/s41598-019-39229-8