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Eliciting the impacts of cellular noise on metabolic trade-offs by quantitative mass imaging

Optimal metabolic trade-offs between growth and productivity are key constraints in strain optimization by metabolic engineering; however, how cellular noise impacts these trade-offs and drives the emergence of subpopulations with distinct resource allocation strategies, remains largely unknown. Her...

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Detalles Bibliográficos
Autores principales: Vasdekis, A. E., Alanazi, H., Silverman, A. M., Williams, C. J., Canul, A. J., Cliff, J. B., Dohnalkova, A. C., Stephanopoulos, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381102/
https://www.ncbi.nlm.nih.gov/pubmed/30783105
http://dx.doi.org/10.1038/s41467-019-08717-w