Metabolomics reveals citric acid secretion in mechanically–stimulated osteocytes is inhibited by high glucose

Osteocytes are the main cells of bone tissue and play a crucial role in bone formation and resorption. Recent studies have indicated that Diabetes Mellitus (DM) affects bone mass and potentially causes higher bone fracture risk. Previous work on osteocyte cell cultures has demonstrated that mechanot...

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Detalles Bibliográficos
Autores principales: Villaseñor, Alma, Aedo-Martín, Daniel, Obeso, David, Erjavec, Igor, Rodríguez-Coira, Juan, Buendía, Irene, Ardura, Juan Antonio, Barbas, Coral, Gortazar, Arancha R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381120/
https://www.ncbi.nlm.nih.gov/pubmed/30783155
http://dx.doi.org/10.1038/s41598-018-38154-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381120/
https://www.ncbi.nlm.nih.gov/pubmed/30783155
http://dx.doi.org/10.1038/s41598-018-38154-6

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