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Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics

In the Alzheimer’s disease (AD) continuum, the prodromal state of mild cognitive impairment (MCI) precedes AD dementia and identifying MCI individuals at risk of progression is important for clinical management. Our goal was to develop generalizable multivariate models that integrate high-dimensiona...

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Detalles Bibliográficos
Autores principales: Varatharajah, Yogatheesan, Ramanan, Vijay K., Iyer, Ravishankar, Vemuri, Prashanthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381141/
https://www.ncbi.nlm.nih.gov/pubmed/30783207
http://dx.doi.org/10.1038/s41598-019-38793-3