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Decoding the 5′ nucleotide bias of PIWI-interacting RNAs

PIWI-interacting RNAs (piRNAs) are at the center of a small RNA-based immune system that defends genomes against the deleterious action of mobile genetic elements (transposons). PiRNAs are highly variable in sequence with extensive targeting potential. Their diversity is restricted by their preferen...

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Detalles Bibliográficos
Autores principales: Stein, Chad B., Genzor, Pavol, Mitra, Sanga, Elchert, Alexandra R., Ipsaro, Jonathan J., Benner, Leif, Sobti, Sushil, Su, Yijun, Hammell, Molly, Joshua-Tor, Leemor, Haase, Astrid D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381166/
https://www.ncbi.nlm.nih.gov/pubmed/30783109
http://dx.doi.org/10.1038/s41467-019-08803-z