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Conditional Dicer1 depletion using Chrnb4-Cre leads to cone cell death and impaired photopic vision

Irreversible photoreceptor cell death is a major cause of blindness in many retinal dystrophies. A better understanding of the molecular mechanisms underlying the progressive loss of photoreceptor cells remains therefore crucial. Abnormal expression of microRNAs (miRNAs) has been linked with the aet...

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Detalles Bibliográficos
Autores principales: Aldunate, Eduardo Zabala, Di Foggia, Valentina, Di Marco, Fabiana, Hervas, Laura Abelleira, Ribeiro, Joana Claudio, Holder, Daniel L., Patel, Aara, Jannini, Tommaso B., Thompson, Dorothy A., Martinez-Barbera, Juan Pedro, Pearson, Rachael A., Ali, Robin R., Sowden, Jane C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381178/
https://www.ncbi.nlm.nih.gov/pubmed/30783126
http://dx.doi.org/10.1038/s41598-018-38294-9