Evaluation of apoptosis imaging biomarkers in a genetic model of cell death

PURPOSE: We have previously developed the caspase-based radiotracer, (18)F-ICMT-11, for PET imaging to monitor treatment response. We further validated (18)F-ICMT-11 specificity in a murine melanoma death-switch tumour model with conditional activation of caspase-3 induced by doxycycline. METHODS: C...

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Detalles Bibliográficos
Autores principales: Vassileva, Vessela, Stribbling, Stephen M., Barnes, Chris, Carroll, Laurence, Braga, Marta, Abrahams, Joel, Heinzmann, Kathrin, Haegeman, Caroline, MacFarlane, Marion, Simpson, Kathryn L., Dive, Caroline, Honeychurch, Jamie, Illidge, Timothy M., Aboagye, Eric O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381199/
https://www.ncbi.nlm.nih.gov/pubmed/30783791
http://dx.doi.org/10.1186/s13550-019-0487-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381199/
https://www.ncbi.nlm.nih.gov/pubmed/30783791
http://dx.doi.org/10.1186/s13550-019-0487-8

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