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Evaluation of apoptosis imaging biomarkers in a genetic model of cell death
PURPOSE: We have previously developed the caspase-based radiotracer, (18)F-ICMT-11, for PET imaging to monitor treatment response. We further validated (18)F-ICMT-11 specificity in a murine melanoma death-switch tumour model with conditional activation of caspase-3 induced by doxycycline. METHODS: C...
Autores principales: | Vassileva, Vessela, Stribbling, Stephen M., Barnes, Chris, Carroll, Laurence, Braga, Marta, Abrahams, Joel, Heinzmann, Kathrin, Haegeman, Caroline, MacFarlane, Marion, Simpson, Kathryn L., Dive, Caroline, Honeychurch, Jamie, Illidge, Timothy M., Aboagye, Eric O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381199/ https://www.ncbi.nlm.nih.gov/pubmed/30783791 http://dx.doi.org/10.1186/s13550-019-0487-8 |
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