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Green tea catechins alleviate autoimmune symptoms and visual impairment in a murine model for human chronic intraocular inflammation by inhibiting Th17-associated pro-inflammatory gene expression

Autoimmune uveitis is a sight-threatening disease mainly caused by dysregulation of immunity. We investigated the therapeutic effects of green tea extract (GTE) and its major component, epigallocatechin-3-gallate (EGCG), on a murine model of experimental autoimmune uveoretinitis (EAU). Oral administ...

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Detalles Bibliográficos
Autores principales: Li, Jian, Yip, Yolanda Wong Ying, Ren, Jialin, Hui, Wing Ki, He, Jing Na, Yu, Qiu Xiao, Chu, Kai On, Ng, Tsz Kin, Chan, Sun On, Pang, Chi Pui, Chu, Wai Kit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381204/
https://www.ncbi.nlm.nih.gov/pubmed/30783194
http://dx.doi.org/10.1038/s41598-019-38868-1