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Transient Knock-Down of Prefrontal DISC1 in Immune-Challenged Mice Causes Abnormal Long-Range Coupling and Cognitive Dysfunction throughout Development

Compromised brain development has been hypothesized to account for mental illness. This concept was underpinned by the function of the molecule disrupted-in-schizophrenia 1 (DISC1), which represents an intracellular hub of developmental processes and has been related to cognitive dysfunction in psyc...

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Detalles Bibliográficos
Autores principales: Xu, Xiaxia, Chini, Mattia, Bitzenhofer, Sebastian H., Hanganu-Opatz, Ileana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381232/
https://www.ncbi.nlm.nih.gov/pubmed/30617212
http://dx.doi.org/10.1523/JNEUROSCI.2170-18.2018