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Infection of B Cell Follicle-Resident Cells by Friend Retrovirus Occurs during Acute Infection and Is Maintained during Viral Persistence

B cell follicles of the spleen and lymph nodes are immune privileged sites and serve as sanctuaries for infected CD4(+) cells in HIV infection. It is assumed that CD8(+) T cell responses promote the establishment of the reservoir, as B cell follicles do not permit CD8(+) T cell entry. Here we analyz...

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Detalles Bibliográficos
Autores principales: Windmann, Sonja, Otto, Lucas, Hrycak, Camilla Patrizia, Malyshkina, Anna, Bongard, Nadine, David, Paul, Gunzer, Matthias, Dittmer, Ulf, Bayer, Wibke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381274/
https://www.ncbi.nlm.nih.gov/pubmed/30782653
http://dx.doi.org/10.1128/mBio.00004-19