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Inhibiting Human Parainfluenza Virus Infection by Preactivating the Cell Entry Mechanism

Paramyxoviruses, specifically, the childhood pathogen human parainfluenza virus type 3, are internalized into host cells following fusion between the viral and target cell membranes. The receptor binding protein, hemagglutinin (HA)-neuraminidase (HN), and the fusion protein (F) facilitate viral fusi...

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Detalles Bibliográficos
Autores principales: Bottom-Tanzer, S. F., Rybkina, K., Bell, J. N., Alabi, C. A., Mathieu, C., Lu, M., Biswas, S., Vasquez, M., Porotto, M., Melero, J. A., Más, V., Moscona, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381285/
https://www.ncbi.nlm.nih.gov/pubmed/30782664
http://dx.doi.org/10.1128/mBio.02900-18