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Can We Improve Vaccine Efficacy by Targeting T and B Cell Repertoire Convergence?
Traditional vaccine development builds on the assumption that healthy individuals have virtually unlimited antigen recognition repertoires of receptors in B cells and T cells [the B cell receptor (BCR) and TCR respectively]. However, there are indications that there are “holes” in the breadth of rep...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381292/ https://www.ncbi.nlm.nih.gov/pubmed/30814993 http://dx.doi.org/10.3389/fimmu.2019.00110 |