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Can We Improve Vaccine Efficacy by Targeting T and B Cell Repertoire Convergence?

Traditional vaccine development builds on the assumption that healthy individuals have virtually unlimited antigen recognition repertoires of receptors in B cells and T cells [the B cell receptor (BCR) and TCR respectively]. However, there are indications that there are “holes” in the breadth of rep...

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Detalles Bibliográficos
Autor principal: Fink, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381292/
https://www.ncbi.nlm.nih.gov/pubmed/30814993
http://dx.doi.org/10.3389/fimmu.2019.00110