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Deletion of Pregnancy Zone Protein and Murinoglobulin-1 Restricts the Pathogenesis of West Nile Virus Infection in Mice

West Nile virus (WNV) is an enveloped positive-stranded RNA virus that causes meningitis, encephalitis, and acute flaccid paralysis in humans. There are no therapeutic agents available for use against WNV infection. Alpha-2 macroglobulin (A2M) is a major plasma proteinase inhibitor that also has imp...

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Detalles Bibliográficos
Autores principales: Krause, Keeton, Azouz, Francine, Nakano, Eileen, Nerurkar, Vivek R., Kumar, Mukesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381297/
https://www.ncbi.nlm.nih.gov/pubmed/30814992
http://dx.doi.org/10.3389/fmicb.2019.00259