ANGPTL4 gene E40K variation protects against obesity‐associated dyslipidemia in participants with obesity

OBJECTIVE: ANGPTL4 inhibits lipoprotein lipase in adipose tissue, regulating plasma triglycerides levels. In persons with obesity plasma ANGPTL4 levels have been positively correlated with body fat mass, TG levels and low HDL. A loss‐of‐function E40K mutation in ANGPTL4 prevents LPL inhibition, resu...

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Detalles Bibliográficos
Autores principales: Bailetti, D., Bertoccini, L., Mancina, R. M., Barchetta, I., Capoccia, D., Cossu, E., Pujia, A., Lenzi, A., Leonetti, F., Cavallo, M. G., Romeo, S., Baroni, M. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381304/
https://www.ncbi.nlm.nih.gov/pubmed/30820332
http://dx.doi.org/10.1002/osp4.311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381304/
https://www.ncbi.nlm.nih.gov/pubmed/30820332
http://dx.doi.org/10.1002/osp4.311

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