Precision medicine review: rare driver mutations and their biophysical classification

How can biophysical principles help precision medicine identify rare driver mutations? A major tenet of pragmatic approaches to precision oncology and pharmacology is that driver mutations are very frequent. However, frequency is a statistical attribute, not a mechanistic one. Rare mutations can als...

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Detalles Bibliográficos
Autores principales: Nussinov, Ruth, Jang, Hyunbum, Tsai, Chung-Jung, Cheng, Feixiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381362/
https://www.ncbi.nlm.nih.gov/pubmed/30610579
http://dx.doi.org/10.1007/s12551-018-0496-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381362/
https://www.ncbi.nlm.nih.gov/pubmed/30610579
http://dx.doi.org/10.1007/s12551-018-0496-2

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