Autoimmune Renal Disease Is Exacerbated by S1P-Receptor-1-Dependent Intestinal Th17 Cell Migration to the Kidney

Th17 cells are most abundant in the gut, where their presence depends on the intestinal microbiota. Here, we examined whether intestinal Th17 cells contribute to extra-intestinal Th17 responses in autoimmune kidney disease. We found high frequencies of Th17 cells in the kidneys of patients with anti...

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Detalles Bibliográficos
Autores principales: Krebs, Christian F., Paust, Hans-Joachim, Krohn, Sonja, Koyro, Tobias, Brix, Silke R., Riedel, Jan-Hendrik, Bartsch, Patricia, Wiech, Thorsten, Meyer-Schwesinger, Catherine, Huang, Jiabin, Fischer, Nicole, Busch, Philipp, Mittrücker, Hans-Willi, Steinhoff, Ulrich, Stockinger, Brigitta, Perez, Laura Garcia, Wenzel, Ulrich O., Janneck, Matthias, Steinmetz, Oliver M., Gagliani, Nicola, Stahl, Rolf A.K., Huber, Samuel, Turner, Jan-Eric, Panzer, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381450/
https://www.ncbi.nlm.nih.gov/pubmed/27851911
http://dx.doi.org/10.1016/j.immuni.2016.10.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381450/
https://www.ncbi.nlm.nih.gov/pubmed/27851911
http://dx.doi.org/10.1016/j.immuni.2016.10.020

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