Modulation of Phospho-CREB by Systemically Administered Recombinant BDNF in the Hippocampus of the R6/2 Mouse Model of Huntington's Disease

Huntington's disease (HD) is an autosomal dominant neurodegenerative disease due to an expansion of a trinucleotide repeats in IT15 gene encoding for the protein huntingtin. Motor dysfunction, cognitive decline, and psychiatric disorder are typical clinical signs of HD. In HD, mutated huntingti...

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Detalles Bibliográficos
Autores principales: Paldino, Emanuela, Giampà, Carmela, Montagna, Elena, Angeloni, Cecilia, Fusco, Francesca R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381568/
https://www.ncbi.nlm.nih.gov/pubmed/30881980
http://dx.doi.org/10.1155/2019/8363274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381568/
https://www.ncbi.nlm.nih.gov/pubmed/30881980
http://dx.doi.org/10.1155/2019/8363274

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