Cargando…

Modulation of Phospho-CREB by Systemically Administered Recombinant BDNF in the Hippocampus of the R6/2 Mouse Model of Huntington's Disease

Huntington's disease (HD) is an autosomal dominant neurodegenerative disease due to an expansion of a trinucleotide repeats in IT15 gene encoding for the protein huntingtin. Motor dysfunction, cognitive decline, and psychiatric disorder are typical clinical signs of HD. In HD, mutated huntingti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Paldino, Emanuela, Giampà, Carmela, Montagna, Elena, Angeloni, Cecilia, Fusco, Francesca R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381568/ https://www.ncbi.nlm.nih.gov/pubmed/30881980 http://dx.doi.org/10.1155/2019/8363274

Ejemplares similares

Systemic Delivery of Recombinant Brain Derived Neurotrophic Factor (BDNF) in the R6/2 Mouse Model of Huntington’s Disease
por: Giampà, Carmela, et al.
Publicado: (2013)

PARP-1 Inhibition Is Neuroprotective in the R6/2 Mouse Model of Huntington’s Disease
por: Cardinale, Antonella, et al.
Publicado: (2015)

Correction: Systemic Delivery of Recombinant Brain Derived Neurotrophic Factor (BDNF) in the R6/2 Mouse Model of Huntington's Disease
por: Giampà, Carmela, et al.
Publicado: (2016)

Selective Sparing of Striatal Interneurons after Poly (ADP-Ribose) Polymerase 1 Inhibition in the R6/2 Mouse Model of Huntington’s Disease
por: Paldino, Emanuela, et al.
Publicado: (2017)

Neuroprotective Effects of Doxycycline in the R6/2 Mouse Model of Huntington’s Disease
por: Paldino, Emanuela, et al.
Publicado: (2019)

Conditioned medium from amniotic cells protects striatal degeneration and ameliorates motor deficits in the R6/2 mouse model of Huntington's disease
por: Giampà, Carmela, et al.
Publicado: (2018)

Modulation of Inflammasome and Pyroptosis by Olaparib, a PARP-1 Inhibitor, in the R6/2 Mouse Model of Huntington’s Disease
por: Paldino, Emanuela, et al.
Publicado: (2020)

Emerging Role of NLRP3 Inflammasome/Pyroptosis in Huntington’s Disease
por: Paldino, Emanuela, et al.
Publicado: (2022)

Pyroptotic cell death in the R6/2 mouse model of Huntington’s disease: new insight on the inflammasome
por: Paldino, Emanuela, et al.
Publicado: (2020)

Inhibition of the Striatal Specific Phosphodiesterase PDE10A Ameliorates Striatal and Cortical Pathology in R6/2 Mouse Model of Huntington's Disease
por: Giampà, Carmela, et al.
Publicado: (2010)

Administration of Phytoceramide Enhances Memory and Upregulates the Expression of pCREB and BDNF in Hippocampus of Mice
por: Lee, Yeonju, et al.
Publicado: (2013)

Inhibition of Necroptosis Rescues SAH-Induced Synaptic Impairments in Hippocampus via CREB-BDNF Pathway
por: Yang, Chunlei, et al.
Publicado: (2019)

Effect of vitamin D supplementation on CREB-TrkB-BDNF pathway in the hippocampus of diabetic rats
por: Nadimi, Hoda, et al.
Publicado: (2020)

Antidepressant effects of crocin and its effects on transcript and protein levels of CREB, BDNF, and VGF in rat hippocampus
por: Vahdati Hassani, Faezeh, et al.
Publicado: (2014)

Reversion of BDNF, Akt and CREB in Hippocampus of Chronic Unpredictable Stress Induced Rats: Effects of Phytochemical, Bacopa Monnieri
por: Hazra, Somoday, et al.
Publicado: (2017)

Estrogen administration attenuates post-stroke depression by enhancing CREB/BDNF/TrkB signaling in the rat hippocampus
por: Jiang, Huigang, et al.
Publicado: (2021)

GPR39 (Zinc Receptor) Knockout Mice Exhibit Depression-Like Behavior and CREB/BDNF Down-Regulation in the Hippocampus
por: Młyniec, Katarzyna, et al.
Publicado: (2015)

Laser Acupuncture Exerts Neuroprotective Effects via Regulation of Creb, Bdnf, Bcl-2, and Bax Gene Expressions in the Hippocampus
por: Yun, Yeong-Chan, et al.
Publicado: (2017)

MeBib Suppressed Methamphetamine Self-Administration Response via Inhibition of BDNF/ERK/CREB Signal Pathway in the Hippocampus
por: Kim, Buyun, et al.
Publicado: (2020)

Neural Stem Cell-Derived Exosomes Revert HFD-Dependent Memory Impairment via CREB-BDNF Signalling
por: Spinelli, Matteo, et al.
Publicado: (2020)

Antidepressive Effects of Kamishoyosan through 5-HT1AReceptor and PKA-CREB-BDNF Signaling in the Hippocampus in Postmenopausal Depression-Model Mice
por: Shimizu, Shoko, et al.
Publicado: (2019)

Decreased BDNF Release in Cortical Neurons of a Knock-in Mouse Model of Huntington’s Disease
por: Yu, Chenglong, et al.
Publicado: (2018)

Alpha-pinene moderates memory impairment induced by kainic acid via improving the BDNF/TrkB/CREB signaling pathway in rat hippocampus
por: Hashemi, Paria, et al.
Publicado: (2023)

Reduced phosphoCREB in Müller glia during retinal degeneration in rd10 mice
por: Dong, Enheng, et al.
Publicado: (2017)

The Utility of BDNF Detection in Assessing Severity of Huntington’s Disease
por: Plinta, Klaudia, et al.
Publicado: (2021)

The effect of different modes of hypobaric hypoxia on the expression of transcription factor pCREB and pro-survival proteins BDNF and BCL-2 in rat neocortex and hippocampus
por: Churilova, Anna, et al.
Publicado: (2015)

Long-term Surgical and Chemical Castration Deteriorates Memory Function Through Downregulation of PKA/CREB/BDNF and c-Raf/MEK/ERK Pathways in Hippocampus
por: Shin, Mal-Soon, et al.
Publicado: (2019)

Antidepressant-Like Effects and Cognitive Enhancement of Coadministration of Chaihu Shugan San and Fluoxetine: Dependent on the BDNF-ERK-CREB Signaling Pathway in the Hippocampus and Frontal Cortex
por: Yan, Lijing, et al.
Publicado: (2020)

Huang-Pu-Tong-Qiao Formula Ameliorates the Hippocampus Apoptosis in Diabetic Cognitive Dysfunction Mice by Activating CREB/BDNF/TrkB Signaling Pathway
por: Ye, Shu, et al.
Publicado: (2021)

Antidepressant effects of aqueous extract of saffron and its effects on CREB, P-CREB, BDNF, and VGF proteins in rat cerebellum
por: Asrari, Najmeh, et al.
Publicado: (2018)

Involvement of BDNF in Age-Dependent Alterations in the Hippocampus
por: Halbach, Oliver von Bohlen und
Publicado: (2010)

Exercise-Mediated Neurogenesis in the Hippocampus via BDNF
por: Liu, Patrick Z., et al.
Publicado: (2018)

Cortical Axonal Secretion of BDNF in the Striatum Is Disrupted in the Mutant-huntingtin Knock-in Mouse Model of Huntington's Disease
por: Park, Hyungju
Publicado: (2018)

Mumefural Improves Recognition Memory and Alters ERK-CREB-BDNF Signaling in a Mouse Model of Chronic Cerebral Hypoperfusion
por: Kim, Min-Soo, et al.
Publicado: (2023)

The Recombinant Human Erythropoietin Administered in Neonatal Rats After Excitotoxic Damage Induces Molecular Changes in the Hippocampus
por: Rivera-Cervantes, Martha Catalina, et al.
Publicado: (2019)

cAMP/PKA-CREB-BDNF signaling pathway in hippocampus mediates cyclooxygenase 2-induced learning/memory deficits of rats subjected to chronic unpredictable mild stress
por: Luo, Ying, et al.
Publicado: (2017)

Melatonin improves brain function in a model of chronic Gulf War Illness with modulation of oxidative stress, NLRP3 inflammasomes, and BDNF-ERK-CREB pathway in the hippocampus
por: Madhu, Leelavathi N., et al.
Publicado: (2021)

Soluble phospho-tau from Alzheimer’s disease hippocampus drives microglial degeneration
por: Sanchez-Mejias, Elisabeth, et al.
Publicado: (2016)

No association between polymorphisms in the BDNF gene and age at onset in Huntington disease
por: Mai, Maren, et al.
Publicado: (2006)

Localization of BDNF mRNA with the Huntington's disease protein in rat brain
por: Ma, Bin, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_qeiotkvcjrsl5dsoilqmabngvb