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Glycine Protects against Hypoxic-Ischemic Brain Injury by Regulating Mitochondria-Mediated Autophagy via the AMPK Pathway

Hypoxic-ischemic encephalopathy (HIE) is detrimental to newborns and is associated with high mortality and poor prognosis. Thus, the primary aim of the present study was to determine whether glycine could (1) attenuate HIE injury in rats and hypoxic stress in PC12 cells and (2) downregulate mitochon...

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Detalles Bibliográficos
Autores principales: Cai, Chen-chen, Zhu, Jiang-hu, Ye, Li-xia, Dai, Yuan-yuan, Fang, Ming-chu, Hu, Ying-ying, Pan, Shu-lin, Chen, Si, Li, Pei-jun, Fu, Xiao-qin, Lin, Zhen-lang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381570/
https://www.ncbi.nlm.nih.gov/pubmed/30881590
http://dx.doi.org/10.1155/2019/4248529