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Functional Variant rs4442975 Modulating FOXA1 Binding Affinity Can Influence Bone Marrow Suppression during Neoadjuvant Chemotherapy for Luminal A Type Breast Cancer

The expression of the transcription factor FOXA1 is associated with the prognosis of estrogen receptor (ER)-positive breast cancer, and the genetic variant rs4442975 can affect FOXA1 function. Therefore, we investigated the association between rs4442975 and the efficacy of neoadjuvant chemotherapy f...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Feng, Zhongxin, Li, Juan, Han, Yanyan, Su, Liyu, Wang, Feng, Yang, Yan, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381587/
https://www.ncbi.nlm.nih.gov/pubmed/30881995
http://dx.doi.org/10.1155/2019/7073498