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NR4A Nuclear Receptors Target Poly-ADP-Ribosylated DNA-PKcs Protein to Promote DNA Repair

Although poly-ADP-ribosylation (PARylation) of DNA repair factors had been well documented, its role in the repair of DNA double-strand breaks (DSBs) is poorly understood. NR4A nuclear orphan receptors were previously linked to DSB repair; however, their function in the process remains elusive. Clas...

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Detalles Bibliográficos
Autores principales: Munnur, Deeksha, Somers, Joanna, Skalka, George, Weston, Ria, Jukes-Jones, Rebekah, Bhogadia, Mohammed, Dominguez, Cyril, Cain, Kelvin, Ahel, Ivan, Malewicz, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381605/
https://www.ncbi.nlm.nih.gov/pubmed/30784586
http://dx.doi.org/10.1016/j.celrep.2019.01.083