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NR4A Nuclear Receptors Target Poly-ADP-Ribosylated DNA-PKcs Protein to Promote DNA Repair
Although poly-ADP-ribosylation (PARylation) of DNA repair factors had been well documented, its role in the repair of DNA double-strand breaks (DSBs) is poorly understood. NR4A nuclear orphan receptors were previously linked to DSB repair; however, their function in the process remains elusive. Clas...
Autores principales: | Munnur, Deeksha, Somers, Joanna, Skalka, George, Weston, Ria, Jukes-Jones, Rebekah, Bhogadia, Mohammed, Dominguez, Cyril, Cain, Kelvin, Ahel, Ivan, Malewicz, Michal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381605/ https://www.ncbi.nlm.nih.gov/pubmed/30784586 http://dx.doi.org/10.1016/j.celrep.2019.01.083 |
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