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MAP7D2 Localizes to the Proximal Axon and Locally Promotes Kinesin-1-Mediated Cargo Transport into the Axon

The motor protein kinesin-1 plays an important role in polarized sorting of transport vesicles to the axon. However, the mechanism by which the axonal entry of kinesin-1-dependent cargo transport is regulated remains unclear. Microtubule-associated protein MAP7 (ensconsin in Drosophila) is an essent...

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Detalles Bibliográficos
Autores principales: Pan, Xingxiu, Cao, Yujie, Stucchi, Riccardo, Hooikaas, Peter Jan, Portegies, Sybren, Will, Lena, Martin, Maud, Akhmanova, Anna, Harterink, Martin, Hoogenraad, Casper C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381606/
https://www.ncbi.nlm.nih.gov/pubmed/30784582
http://dx.doi.org/10.1016/j.celrep.2019.01.084