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Staphylococcus aureus with an erm-mediated constitutive macrolide-lincosamide-streptogramin B resistance phenotype has reduced susceptibility to the new ketolide, solithromycin

BACKGROUND: Solithromycin, the fourth generation of ketolides, has been demonstrated potent antibacterial effect against commonly-isolated gram-positive strains. However, Staphylococcus aureus (S. aureus) strains with a higher solithromycin MIC have already been emerged, the mechanism of which is un...

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Detalles Bibliográficos
Autores principales: Yao, Weiming, Xu, Guangjian, Li, Duoyun, Bai, Bing, Wang, Hongyan, Cheng, Hang, Zheng, Jinxin, Sun, Xiang, Lin, Zhiwei, Deng, Qiwen, Yu, Zhijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381629/
https://www.ncbi.nlm.nih.gov/pubmed/30782125
http://dx.doi.org/10.1186/s12879-019-3779-8