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miR-96 exerts carcinogenic effect by activating AKT/GSK-3β/β-catenin signaling pathway through targeting inhibition of FOXO1 in hepatocellular carcinoma
BACKGROUND: The aim of this research was to investigate the mechanism of miR-96 affecting hepatocellular carcinoma (HCC). METHODS: mRNA and protein expression was detected by qRT-PCR and Western blot, respectively. HepG2 cells were transfected and grouped as follows: miR-NC group, miR-mimics group,...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381685/ https://www.ncbi.nlm.nih.gov/pubmed/30828264 http://dx.doi.org/10.1186/s12935-019-0756-7 |