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miR-96 exerts carcinogenic effect by activating AKT/GSK-3β/β-catenin signaling pathway through targeting inhibition of FOXO1 in hepatocellular carcinoma

BACKGROUND: The aim of this research was to investigate the mechanism of miR-96 affecting hepatocellular carcinoma (HCC). METHODS: mRNA and protein expression was detected by qRT-PCR and Western blot, respectively. HepG2 cells were transfected and grouped as follows: miR-NC group, miR-mimics group,...

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Detalles Bibliográficos
Autores principales: Yang, Nanmu, Zhou, Jinxue, Li, Qingjun, Han, Feng, Yu, Zujiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381685/
https://www.ncbi.nlm.nih.gov/pubmed/30828264
http://dx.doi.org/10.1186/s12935-019-0756-7