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CCDC6 and USP7 expression levels suggest novel treatment options in high-grade urothelial bladder cancer

BACKGROUND: The muscle invasive form of urothelial bladder cancer (UBC) is a deadly disease. Currently, the therapeutic approach of UBC is mostly based on surgery and standard chemotherapy. Biomarkers to establish appropriate drugs usage are missing. Deficiency of the tumor suppressor CCDC6 determin...

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Detalles Bibliográficos
Autores principales: Morra, Francesco, Merolla, Francesco, Criscuolo, Daniela, Insabato, Luigi, Giannella, Riccardo, Ilardi, Gennaro, Cerrato, Aniello, Visconti, Roberta, Staibano, Stefania, Celetti, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381716/
https://www.ncbi.nlm.nih.gov/pubmed/30786932
http://dx.doi.org/10.1186/s13046-019-1087-1