Extracellular acidification-induced CXCL8 production through a proton-sensing receptor OGR1 in human airway smooth muscle cells: a response inhibited by dexamethasone

BACKGROUND: Human airway smooth muscle cells (ASMCs) contribute to bronchial contraction and airway hyperresponsiveness in patients with bronchial asthma. They also generate cytokines, chemokines, and matricellular proteins. Ovarian cancer G protein-coupled receptor 1 (OGR1) senses extracellular pro...

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Detalles Bibliográficos
Autores principales: Kadowaki, Maiko, Yamada, Hidenori, Sato, Koichi, Shigemi, Hiroko, Umeda, Yukihiro, Morikawa, Miwa, Waseda, Yuko, Anzai, Masaki, Kamide, Yosuke, Aoki-Saito, Haruka, Hisada, Takeshi, Okajima, Fumikazu, Ishizuka, Tamotsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381743/
https://www.ncbi.nlm.nih.gov/pubmed/30828266
http://dx.doi.org/10.1186/s12950-019-0207-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381743/
https://www.ncbi.nlm.nih.gov/pubmed/30828266
http://dx.doi.org/10.1186/s12950-019-0207-1

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