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Autism and Schizophrenia-Associated CYFIP1 Regulates the Balance of Synaptic Excitation and Inhibition

Altered excitatory/inhibitory (E/I) balance is implicated in neuropsychiatric and neurodevelopmental disorders, but the underlying genetic etiology remains poorly understood. Copy number variations in CYFIP1 are associated with autism, schizophrenia, and intellectual disability, but its role in regu...

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Detalles Bibliográficos
Autores principales: Davenport, Elizabeth C., Szulc, Blanka R., Drew, James, Taylor, James, Morgan, Toby, Higgs, Nathalie F., López-Doménech, Guillermo, Kittler, Josef T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381785/
https://www.ncbi.nlm.nih.gov/pubmed/30784587
http://dx.doi.org/10.1016/j.celrep.2019.01.092