Dynamics of the Eukaryotic Replicative Helicase at Lagging-Strand Protein Barriers Support the Steric Exclusion Model

Progression of DNA replication depends on the ability of the replisome complex to overcome nucleoprotein barriers. During eukaryotic replication, the CMG helicase translocates along the leading-strand template and unwinds the DNA double helix. While proteins bound to the leading-strand template effi...

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Detalles Bibliográficos
Autores principales: Kose, Hazal B., Larsen, Nicolai B., Duxin, Julien P., Yardimci, Hasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381796/
https://www.ncbi.nlm.nih.gov/pubmed/30784593
http://dx.doi.org/10.1016/j.celrep.2019.01.086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381796/
https://www.ncbi.nlm.nih.gov/pubmed/30784593
http://dx.doi.org/10.1016/j.celrep.2019.01.086

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