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Recent advances in understanding the regulation of metalloproteinases

Metalloproteinases remain important players in arthritic disease, in part because members of this large enzymatic family, namely matrix metalloproteinase-1 (MMP-1) and MMP-13, are responsible for the irreversible degradation of articular cartilage collagen. Although direct inhibition of MMPs fell ou...

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Detalles Bibliográficos
Autores principales: Young, David A., Barter, Matt J., Wilkinson, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381797/
https://www.ncbi.nlm.nih.gov/pubmed/30828429
http://dx.doi.org/10.12688/f1000research.17471.1