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Sexual dimorphism of acute doxorubicin-induced nephrotoxicity in C57Bl/6 mice

Doxorubicin (DOX) is a chemotherapeutic agent that has been reported to cause nephrotoxicity in rodent models and to a lesser degree in cancer patients. Female rodents have been shown to be protected against several features of DOX-induced nephrotoxicity. Nevertheless, the underlying mechanisms of t...

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Detalles Bibliográficos
Autores principales: Grant, Marianne K. O., Seelig, Davis M., Sharkey, Leslie C., Choi, Wan S. V., Abdelgawad, Ibrahim Y., Zordoky, Beshay N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382134/
https://www.ncbi.nlm.nih.gov/pubmed/30785938
http://dx.doi.org/10.1371/journal.pone.0212486