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Metal based donepezil analogues designed to inhibit human acetylcholinesterase for Alzheimer’s disease
Among neurodegenerative disorders, Alzheimer’s disease (AD) is one of the most common disorders showing slow progressive cognitive decline. Targeting acetylcholinesterase (AChE) is one of the major strategies for AD therapeutics, as cholinergic pathways in the cerebral cortex and basal forebrain are...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382135/ https://www.ncbi.nlm.nih.gov/pubmed/30785927 http://dx.doi.org/10.1371/journal.pone.0211935 |