Strand break-induced replication fork collapse leads to C-circles, C-overhangs and telomeric recombination

Telomerase-independent ALT (alternative lengthening of telomeres) cells are characterized by high frequency of telomeric homologous recombination (HR), C-rich extrachromosomal circles (C-circles) and C-rich terminal 5' overhangs (C-overhangs). However, underlying mechanism is poorly understood....

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Detalles Bibliográficos
Autores principales: Zhang, Tianpeng, Zhang, Zepeng, Shengzhao, Gong, Li, Xiaocui, Liu, Haiying, Zhao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382176/
https://www.ncbi.nlm.nih.gov/pubmed/30716077
http://dx.doi.org/10.1371/journal.pgen.1007925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382176/
https://www.ncbi.nlm.nih.gov/pubmed/30716077
http://dx.doi.org/10.1371/journal.pgen.1007925

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