A genetic variant associated with multiple sclerosis inversely affects the expression of CD58 and microRNA-548ac from the same gene

Genome-wide association studies have identified more than 200 genetic variants to be associated with an increased risk of developing multiple sclerosis (MS). Still, little is known about the causal molecular mechanisms that underlie the genetic contribution to disease susceptibility. In this study,...

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Detalles Bibliográficos
Autores principales: Hecker, Michael, Boxberger, Nina, Illner, Nicole, Fitzner, Brit, Schröder, Ina, Winkelmann, Alexander, Dudesek, Ales, Meister, Stefanie, Koczan, Dirk, Lorenz, Peter, Thiesen, Hans-Jürgen, Zettl, Uwe Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382214/
https://www.ncbi.nlm.nih.gov/pubmed/30730892
http://dx.doi.org/10.1371/journal.pgen.1007961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382214/
https://www.ncbi.nlm.nih.gov/pubmed/30730892
http://dx.doi.org/10.1371/journal.pgen.1007961

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